{"id":301907,"date":"2022-01-20T14:39:51","date_gmt":"2022-01-20T14:39:51","guid":{"rendered":"https:\/\/www.merieuxnutrisciences.com\/food-packaging\/packaging-laboratory-testing\/nias-screening\/"},"modified":"2026-11-11T08:13:18","modified_gmt":"2026-11-11T08:13:18","slug":"nias-screening","status":"publish","type":"page","link":"https:\/\/www.merieuxnutrisciences.com\/za\/food-packaging\/packaging-laboratory-testing\/nias-screening\/","title":{"rendered":"NIAS Screening"},"content":{"rendered":"\n<div class=\"page-header-block-wrapper fullwidth-block\">\n    <div class=\"acf-page-header\" style=\"background-image: url('https:\/\/www.merieuxnutrisciences.com\/wp-content\/uploads\/2022\/06\/nias-screening.png'); \">\n        <div class=\"overlay\"><\/div>\n        <div class=\"acf-page-header-container\">\n                            <div class=\"image-wrapper\">\n                    <img decoding=\"async\" src=\"https:\/\/www.merieuxnutrisciences.com\/wp-content\/uploads\/2024\/02\/nias-screening-white.png\" alt=\"Icon\" \/>\n                <\/div>\n                        <h1>NIAS Screening<\/h1>\n        <\/div>\n    <\/div>\n<\/div>\n\n<style>\n.page-header-block-wrapper{\n    margin-bottom: 60px;\n}\n\n.fullwidth-block {\n    max-width: none !important;\n    width: 100vw !important;\n    position: relative;\n    padding:0px;\n    left: 50%;\n    right: 50%;\n    margin-left: -50vw;\n    margin-right: -50vw;\n}\n\n.acf-page-header {\n    background-size: cover;\n    background-position: center;\n    display: flex;\n    position: relative;\n    min-height: 250px; \n}\n\n.acf-page-header-container{\n    margin: 0 auto;\n    padding: 48px 24px;\n    display: flex;\n    flex-direction: column;\n    justify-content: end;\n    align-items: center;\n}\n\n.acf-page-header .overlay {\n    position: absolute;\n    top: 0;\n    left: 0;\n    right: 0;\n    bottom: 0;\n    background: linear-gradient(to top, var(--global-palette4), transparent);\n    z-index: 1;\n}\n\n.acf-page-header-container .image-wrapper{\n    position:relative;\n    height: 70px;\n    width: 70px;\n    background: var(--global-palette4);\n    border-radius: 50%;\n    z-index: 1;\n}\n\n.acf-page-header-container img{\n    position: absolute;\n    top: 50%;\n    left: 50%;\n    transform: translate(-50%, -50%);\n    max-width:40px;\n    z-index: 2;\n}\n\n.acf-page-header h1 {\n    display:block;\n    position: relative;\n    z-index: 2;\n    color:white;\n    text-align: center;\n}\n\n@media (min-width: 1025px) {\n    .acf-page-header-container{\n        width: 1290px;\n    }\n    \n}\n\n@media (max-width: 1024px) {\n    .acf-page-header-container {\n        align-self: end;\n    }\n    .acf-page-header .overlay {\n        background: linear-gradient(to top, var(--global-palette4), transparent);\n    }\n}\n\n@media (max-width: 768px) {\n    .acf-page-header .overlay {\n        background: linear-gradient(to top, var(--global-palette4), transparent);\n    }\n    .acf-page-header h1 {\n        font-size:28px;\n    }\n}\n\n<\/style>\n\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Non Intentionally Added Substances (NIAS)<\/strong>, are not constituents or functional additives, but rather originate from <strong>polymer <\/strong>and <strong>additive <\/strong>degradation or impurities in raw materials.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As demand for high-performance packaging grows, designers are creating new shapes and utilizing innovative materials. This trend inevitably leads manufacturers to address NIAS, posing a continuous <strong>analytical challenge<\/strong> due to the introduction of many <strong>new additives<\/strong>.<\/p>\n\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-301907_137b25-78 .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-301907_137b25-78 .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-301907_137b25-78\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><hr class=\"kt-divider\"\/><\/div><\/div>\n\n\n\n<h2 id=\"h-regulatory-framework-and-guidelines-for-nias\" class=\"wp-block-heading\"><strong>Regulatory Framework and Guidelines<\/strong> for NIAS<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">According to <a href=\"http:\/\/data.europa.eu\/eli\/reg\/2004\/1935\/oj\" target=\"_blank\" rel=\"noopener\">Regulation (EC) no. 1935\/2004<\/a>, <a href=\"https:\/\/www.merieuxnutrisciences.com\/packaging\/food-contact-materials\/\"><strong>food contact materials<\/strong><\/a> should not <strong>endanger human health<\/strong>, <strong>alter food composition<\/strong>, or <strong>deteriorate organoleptic characteristics<\/strong> under normal conditions. Consequently, <strong>monitoring<\/strong> packaging material components that could migrate into food becomes essential for ensuring quality and safety.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NIAS screening in <strong>packaging <\/strong>becomes particularly useful under these circumstances. These substances were first mentioned in <a href=\"http:\/\/data.europa.eu\/eli\/reg\/2011\/10\/oj\" target=\"_blank\" rel=\"noreferrer noopener\">Regulation (EU) no. 10\/2011<\/a>, emphasizing their relevance to risk assessment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">EFSA underlined that the approach used for IAS (Intentionally Added Substances) could, in principle, apply to NIAS, as it should guarantee the same degree of safety for all migrating substances. <a href=\"https:\/\/ilsi.eu\/\" target=\"_blank\" rel=\"noreferrer noopener\">ILSI Europe<\/a> drew up the first European Guidelines. While these guidelines center on the EU, adopting them offers significant benefits for exporters navigating international markets.<\/p>\n\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-301907_051bf8-7e .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-301907_051bf8-7e .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-301907_051bf8-7e\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><hr class=\"kt-divider\"\/><\/div><\/div>\n\n\n\n<h2 id=\"h-nias-screening-options\" class=\"wp-block-heading\"><strong>NIAS Screening Options<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">M\u00e9rieux NutriSciences offers a comprehensive array of options for NIAS screening, encompassing both <strong>targeted <\/strong>and <strong>non-targeted analyses<\/strong> to identify a wide range of substances, including <strong>elements<\/strong>, <strong>volatile<\/strong>, <strong>semi-volatile<\/strong>, and <strong>non-volatile <\/strong>compounds. This approach allows for the creation of a tailored analytical plan based on specific matrix requirements.<\/p>\n\n\n\n<h3 id=\"h-sophisticated-analytical-approach\" class=\"wp-block-heading\"><strong>Sophisticated Analytical Approach<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">To address the growing demand for NIAS screening, M\u00e9rieux NutriSciences employs a sophisticated <strong>3-step approach<\/strong> for non-volatile compounds, utilizing <strong>liquid chromatography<\/strong> coupled to <strong>high resolution mass spectrometry<\/strong> (UHPLC ESI-MS\/HRMS &#8211; Q-Orbitrap). This methodology ensures superior resolution, accuracy, and access to an extensive library of compounds.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>The approach comprises:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li style=\"font-size:18px\">A quantitative targeted analysis focusing on the specific migration of nearly 70 common packaging constituents.<\/li>\n\n\n\n<li style=\"font-size:18px\">A semi-quantitative targeted analysis of approximately 1500 substances facilitated by internal standards and library checks.<\/li>\n\n\n\n<li style=\"font-size:18px\">A semi-quantitative non-targeted analysis to identify any remaining unidentified molecules.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">The suggested analytical method guarantees high resolution, increased accuracy and access to a library which is constantly updated.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The approach proposed by M\u00e9rieux NutriSciences allows you to&nbsp;obtain food contact material risk assessment by <strong>chemical screening<\/strong> and <strong>bioassays<\/strong>:<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6af6a48951557&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6af6a48951557\" class=\"aligncenter size-full is-resized wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"980\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on--pointerdown=\"actions.preloadImage\" data-wp-on--pointerenter=\"actions.preloadImageWithDelay\" data-wp-on--pointerleave=\"actions.cancelPreload\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/www.merieuxnutrisciences.com\/wp-content\/uploads\/2024\/02\/homepage_slide_packaging-2.jpg\" alt=\"\" class=\"wp-image-77533\" style=\"width:800px;height:auto\"\/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\tdata-wp-bind--aria-label=\"state.thisImage.triggerButtonAriaLabel\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.thisImage.buttonRight\"\n\t\t\tdata-wp-style--top=\"state.thisImage.buttonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><\/figure>\n<\/div>\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-301907_9f057c-80 .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-301907_9f057c-80 .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-301907_9f057c-80\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><hr class=\"kt-divider\"\/><\/div><\/div>\n\n\n\n<h3 id=\"h-complementary-testing\" class=\"wp-block-heading\"><strong>Complementary Testing<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Endocrine disruptors testing is complementary to NIAS chemical approach&nbsp;<\/strong>to better assess the safety of food contact materials.<\/p>\n\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-301907_de3749-5e .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-301907_de3749-5e .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-301907_de3749-5e\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><hr class=\"kt-divider\"\/><\/div><\/div>\n\n\n\n<div class=\"wp-block-columns are-vertically-aligned-center is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Get more info on our expertise:<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div style=\"--wp--block-button--width: 100;\" class=\"wp-block-button has-custom-width wp-block-button__width wp-block-button__width-100\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.merieuxnutrisciences.com\/za\/contact\/\"><strong>Contact us<\/strong><\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-6b01c2ec wp-block-columns-is-layout-flex\" style=\"border-style:none;border-width:0px;margin-top:0;margin-bottom:0;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">\n<div class=\"wp-block-column is-vertically-aligned-center has-theme-palette-8-background-color has-background is-layout-flow wp-block-column-is-layout-flow\" style=\"border-radius:8px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\">\n<div class=\"wp-block-columns are-vertically-aligned-center is-not-stacked-on-mobile is-layout-flex wp-container-core-columns-is-layout-5dc627e1 wp-block-columns-is-layout-flex\" style=\"margin-top:0;margin-bottom:0\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:90px\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\" style=\"margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px\"><img loading=\"lazy\" decoding=\"async\" width=\"1072\" height=\"1520\" src=\"https:\/\/www.merieuxnutrisciences.com\/wp-content\/uploads\/2025\/12\/Capture-decran-2025-12-29-a-15.21.59.png\" alt=\"\" class=\"wp-image-247803\" style=\"width:auto;height:125px\" srcset=\"https:\/\/www.merieuxnutrisciences.com\/wp-content\/uploads\/2025\/12\/Capture-decran-2025-12-29-a-15.21.59.png 1072w, https:\/\/www.merieuxnutrisciences.com\/wp-content\/uploads\/2025\/12\/Capture-decran-2025-12-29-a-15.21.59-212x300.png 212w, https:\/\/www.merieuxnutrisciences.com\/wp-content\/uploads\/2025\/12\/Capture-decran-2025-12-29-a-15.21.59-722x1024.png 722w, https:\/\/www.merieuxnutrisciences.com\/wp-content\/uploads\/2025\/12\/Capture-decran-2025-12-29-a-15.21.59-768x1089.png 768w\" sizes=\"auto, (max-width: 1072px) 100vw, 1072px\" \/><\/figure>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:80%\"><style>.wp-block-kadence-advancedheading.kt-adv-heading301907_c597da-8d, .wp-block-kadence-advancedheading.kt-adv-heading301907_c597da-8d[data-kb-block=\"kb-adv-heading301907_c597da-8d\"]{margin-top:0px;margin-bottom:var(--global-kb-spacing-xxs, 0.5rem);font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading301907_c597da-8d mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading301907_c597da-8d[data-kb-block=\"kb-adv-heading301907_c597da-8d\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading301907_c597da-8d img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading301907_c597da-8d[data-kb-block=\"kb-adv-heading301907_c597da-8d\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<p class=\"kt-adv-heading301907_c597da-8d wp-block-kadence-advancedheading has-theme-palette-3-color has-text-color\" data-kb-block=\"kb-adv-heading301907_c597da-8d\">For more info on our NIAS services:<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-36a1675f wp-block-buttons-is-layout-flex\" style=\"margin-top:0;margin-bottom:0\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-text-align-left has-custom-font-size wp-element-button\" href=\"https:\/\/www.merieuxnutrisciences.com\/wp-content\/uploads\/2025\/12\/mxns_NIAS_FL0817_3_ENG_web.pdf\" style=\"font-size:18px\" target=\"_blank\" rel=\"noreferrer noopener\">Download our brochure<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n<div class=\"page-cards-block-wrapper fullwidth-block\">   \n    <div class=\"page-cards-title-container\"> \n        <h2>Packaging Testing Services<\/h2>    \n    <\/div>\n    <div class=\"full-width-row-page-cards-wrapper\">\n        <div class=\"page-cards-container\">\n                                            <a href=\"https:\/\/www.merieuxnutrisciences.com\/za\/food-packaging\/packaging-laboratory-testing\/\" class=\"card\">\n                                            <img decoding=\"async\" src=\"https:\/\/www.merieuxnutrisciences.com\/wp-content\/uploads\/2024\/02\/packaging-testing-blue-1.png\" alt=\"Packaging Laboratory Testing\" class=\"card-icon\"\/>\n                                        <div class=\"card-content\">\n                        <span>Packaging Laboratory Testing<\/span>\n                    <\/div>\n                <\/a>\n                                <\/div>\n    <\/div>\n<\/div>    \n   \n\n<style>\n.fullwidth-block {\n    max-width: none !important;\n    width: 100vw !important;\n    position: relative;\n    padding:0px;\n    \/* left: 50%;\n    right: 50%;\n    margin-left: -50vw;\n    margin-right: -50vw; *\/\n}\n\n.page-cards-title-container{\n    max-width: 1290px;\n    margin: 100px auto 150px auto;\n    padding-left: var(--global-content-edge-padding);\n    padding-right: var(--global-content-edge-padding);\n}\n.page-cards-title-container h2{\n    color:var(--global-palette4);\n    text-align: center;\n}\n.full-width-row-page-cards-wrapper{\n    background-color: var(--global-palette4);\n}\n.page-cards-container{\n    max-width:1290px;\n    margin: 0 auto;\n    display: flex;\n    gap: 20px;\n    align-items: center;\n    justify-content: center;\n    padding: 0 12px;\n    flex-wrap: wrap;\n}\n.card {\n    display: flex;\n    transform: translate(0px, -100px);\n    flex-direction: column;\n    align-items: center;\n    justify-content: 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As demand for high-performance packaging grows, designers are creating new shapes and utilizing innovative materials. This trend inevitably leads manufacturers to address NIAS, posing a continuous analytical challenge due to the&#8230;<\/p>\n","protected":false},"author":23,"featured_media":268910,"parent":300858,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"service-page-testing-blue.php","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"folder":[],"class_list":["post-301907","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"taxonomy_info":[],"featured_image_src_large":["https:\/\/www.merieuxnutrisciences.com\/wp-content\/uploads\/2022\/06\/nias-screening.png",1024,299,false],"author_info":{"display_name":"Alice Marcolin","author_link":"https:\/\/www.merieuxnutrisciences.com\/za\/author\/alice-marcolin\/"},"comment_info":0,"_links":{"self":[{"href":"https:\/\/www.merieuxnutrisciences.com\/za\/wp-json\/wp\/v2\/pages\/301907","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.merieuxnutrisciences.com\/za\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.merieuxnutrisciences.com\/za\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.merieuxnutrisciences.com\/za\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/www.merieuxnutrisciences.com\/za\/wp-json\/wp\/v2\/comments?post=301907"}],"version-history":[{"count":1,"href":"https:\/\/www.merieuxnutrisciences.com\/za\/wp-json\/wp\/v2\/pages\/301907\/revisions"}],"predecessor-version":[{"id":302115,"href":"https:\/\/www.merieuxnutrisciences.com\/za\/wp-json\/wp\/v2\/pages\/301907\/revisions\/302115"}],"up":[{"embeddable":true,"href":"https:\/\/www.merieuxnutrisciences.com\/za\/wp-json\/wp\/v2\/pages\/300858"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.merieuxnutrisciences.com\/za\/wp-json\/wp\/v2\/media\/268910"}],"wp:attachment":[{"href":"https:\/\/www.merieuxnutrisciences.com\/za\/wp-json\/wp\/v2\/media?parent=301907"}],"wp:term":[{"taxonomy":"folder","embeddable":true,"href":"https:\/\/www.merieuxnutrisciences.com\/za\/wp-json\/wp\/v2\/folder?post=301907"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}